Staging systems for hepatocellular carcinoma: Current status and future perspectives

来源 :World Journal of Hepatology | 被引量 : 0次 | 上传用户:starfox_vip
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Hepatocellular carcinoma(HCC) is a major health concern worldwide and the third cause of cancer-related death. Despite advances in treatment as well as careful surveillance programs, the mortality rates in most countries are very high. In contrast to other cancers, the prognosis and treatment of HCC depend on the tumor burden in addition to patient’s underlying liver disease and liver functional reserve. Moreover, thereis considerable geographic and institutional variation in both risk factors attributable to the underlying liver diseases and the management of HCC. Therefore, although many staging and/or scoring systems have been proposed, there is currently no globally accepted system for HCC due to the extreme heterogeneity of the disease. The aim of this review is to focus on currently available staging systems as well as those newly reported in the literatures since 2012. Moreover, we describe problems with currently available staging systems and attempts to modify and/or add variables to existing staging systems. The prognosis in treatment as well as careful surveillance programs, the mortality rate in most countries are very high. In contrast to other cancers, the prognosis and treatment of HCC depend on the tumor burden in addition to patient’s underlying liver disease and liver functional reserve. Moreover, thereis considerable geographic and institutional variation in both underlying liver diseases and liver functional reserve. Therefore, although many staging and / or scoring systems have been proposed, there is currently no globally accepted system for HCC due to the extreme heterogeneity of the disease. The aim of this review is to focus on currently available staging systems as well as those newly reported in the liteographic since 2012. Moreover, we describe problems with currently available staging systems and attempts to modify and / or add varia bles to existing staging systems.
其他文献
非洲菊是世界五大切花之一,深受人们的喜爱。随着非洲菊组织培养技术的逐步发展和基因工程技术在各种花卉上的广泛应用,非洲菊遗传转化育种作为一种重要的育种手段受到越来越
披碱草属牧草是我国很多草原地区极其重要的牧草资源,具有适应性强,品质优良,产草量高,种子产量高,抗寒耐旱性强的特点,但目前对披碱草属牧草的研究多集中在干旱、寒冷等逆境
很久很久以前,强大的帝国正在黑武士的率领下围攻一颗冰雪星球,义军的反击在巨大的四足机械怪物前显得微不足道.节节败退之际,年轻的绝地武士驾驶着一种奇特的飞行器用前所未
期刊
全球气候变化和人类活动造成的土地利用/覆被变化(LUCC)对区域乃至全球水文循环产生的影响日益加深。河川径流是水文循环的重要环节,探究流域径流对气候和土地利用/覆被变化的
白桦(Betula platyphylla)是一个经济价值较高的树种,目前关于白桦的研究已经取得了可喜的进展,但是关于白桦花发育基因的研究才刚刚起步。为了更多的了解白桦花期基因表达背景
本文对从澳大利亚引种到四川栽培的巨桉人工林,按GB1927~1942-91《木材物理力学性质试验方法》的规定,进行了木材物理力学性质研究。研究的木材物理性质有木材的密度、含水率、
本文从功能需求、解决方案、视频系统等方面介绍了江苏广电总台100A演播室高清系统的设计和建设。 This article introduces the design and construction of the high defi
盐碱地是地球上重要的土地资源。生物治理是开发和利用盐碱地的有效途径,了解植物的耐盐机理可以培育更优的耐盐品种以及寻找提高植物耐盐性的途径和方法,有利于盐碱土的治理
森林资源一直以来都是一个国家维持生态平衡和国民经济稳定发展的根本。林业部门在对森林资源培育维护之外,还通过木材市场的交易行为向社会提供林木资源以满足社会生产生活
苏词的编年工作经过几代学人的不懈努力,已经取得了丰硕的成果,绝大数的作品已有编年,然已编作品中只有过半取得共识,尚有大量未编而可编、已编而误编者,故苏词编年还有工作