肝移植已成为治疗成人和儿童终末期肝病的有效方法,而儿童肝移植在整个肝移植的发展史中有着举足轻重的地位。1963年3月1日美国Starzl完成人类第一例肝移植,病人是先天性胆道闭锁的3岁儿童。1970年完成的1例儿童肝移植是保持目前生存时间最长的记录(44年)。另外一些新技术如劈离式肝移植[1]、活体肝移植[2]等的开展,最初也是为了缓解儿童肝脏紧缺的矛盾。随着免疫抑制剂 Liver transplantation has become an effective treatment for end-stage liver disease in adults and children, and childhood liver transplantation plays a decisive role in the overall history of liver transplantation. March 1, 1963 Starzl completed the first human liver transplantation in humans. The patient was a 3-year-old child with congenital biliary atresia. One child with liver transplantation completed in 1970 was the longest surviving record (44 years). Other new technologies, such as split liver transplantation [1], living donor liver transplantation [2], etc., were also initiated initially to alleviate the contradictions in children with liver shortness. With immunosuppressive agents