将大明湖水样经XAD-2树脂富集萃取物,用Ames试验检测了其致突变性。结果表明,湖心水和出口水有较明显的致突变性,有碱基置换型和移码型致突变作用,并有不经S-9混合物活化而直接致突变的可能。新菌株TA_(102)在加S-9混合物后敏感性增强,在研究地面水致突变作用中有实用意义。 The water extract of Daming Lake was enriched by XAD-2 resin and its mutagenicity was tested by Ames test. The results showed that the lake water and outlet water had obvious mutagenicity, base substitution and frameshift mutagenesis, and could be directly mutated without S-9 mixture activation. The new strain TA_ (102) enhanced sensitivity after adding S-9 mixture, which has practical significance in studying the mutagenic effect of surface water.