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目的 探讨免疫球蛋白治疗川崎病及其心血管病变的疗效。方法 川崎病患儿 30例 ,按治疗方法不同分为两组 ,两组均给予阿司匹林等治疗。观察组另给予大剂量免疫球蛋白 0 .4 g/ (kg·d) ,连续静滴5d ,观察用药后两组患儿的热程、异常心电图和增高血小板数恢复时间及冠状动脉扩张发生率。结果 观察组患儿治疗后热程、异常心电图和增高血小板数恢复时间及冠状动脉扩张发生率与对照组相比有显著差异 (P <0 .0 5 )。结论 大剂量免疫球蛋白治疗川崎病 ,不但明显缓解临床症状 ,而且还对川崎病心血管病变的防治具有重要意义
Objective To investigate the therapeutic effect of immunoglobulin on Kawasaki disease and its cardiovascular diseases. Methods Thirty children with Kawasaki disease were divided into two groups according to the different treatment methods. Both groups were given aspirin and other treatments. The observation group was given another high-dose immunoglobulin 0. 4 g / (kg · d), continuous intravenous drip 5d, observed after treatment in two groups of children with fever, abnormal ECG and increased platelet recovery time and the incidence of coronary artery dilatation . Results In the observation group, there was a significant difference in the thermal pathology, abnormal electrocardiogram, recovery time of elevated platelet count and coronary artery dilation compared with the control group (P <0.05). Conclusion High-dose immunoglobulin treatment of Kawasaki disease, not only significantly alleviate the clinical symptoms, but also for the prevention and treatment of Kawasaki disease is of great significance