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目的:分析我院2006～2008年上报的药物不良反应(ADR)发生规律和特点。方法:对上报的530例药品不良反应分别从患者年龄、给药途径、药品种类、ADR临床表现等方面进行回顾性分析与评价。结果:530例ADR报告中共涉及13大类药物,药品种类共184种,其中抗感染药物引起的ADR最多,占34.15%;给药途径中静脉用药引起的ADR 399例,占75.28%;ADR临床表现主要为皮肤及其附件损害,占31.70%。结论:必须重视药品不良反应监测工作,加强药师与临床的沟通交流,减少或避免ADR的发生。
Objective: To analyze the regularity and characteristics of adverse drug reaction (ADR) reported in our hospital from 2006 to 2008. Methods: A total of 530 reported adverse drug reactions were retrospectively analyzed and evaluated in terms of patient’s age, route of administration, type of drug, and clinical manifestations of ADR. Results: A total of 530 categories of ADRs were reported involving a total of 184 kinds of drugs, of which there were 184 kinds of drugs. Among them, anti-infectives caused the most ADR, accounting for 34.15%; 399 cases of ADR caused by intravenous drug administration, accounting for 75.28%; ADR clinical The main performance of the skin and its accessories damage, accounting for 31.70%. Conclusion: We must attach great importance to the monitoring of adverse drug reactions, to enhance communication and exchange between pharmacists and clinics to reduce or avoid the occurrence of ADR.