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目的运用品管圈管理方法来降低无菌包不合格件数。方法利用品管圈活动回顾性分析2013年7月1日~28日本院消毒供应中心消毒灭菌的2500个无菌物品包缺失情况，针对缺失发生的原因提出相应的对策措施，并于2013年10月1日~28日严格执行。比较品管圈活动干预前后无菌包不合格件数。结果对2013年10月1日~28日消毒灭菌的2500个无菌包进行干预后无菌包不合格件数由活动前15.75件/w降至活动后的5.25件/w，与同年7月相比较有显著下降，差异具有统计学意义(<0.01)。结论品管圈活动在降低无菌包不合格件数中，取得满意效果，值得推广。全体圈成员对解决问题的能力、责任感、凝聚力、积极性、沟通配合、愉悦感、品管手法、和谐程度有了提高。“,”Objective To apply the qc circle management methods to reduce the unqualified aseptic package number. Methods Using quality management circle activity 1 ~ 28 July 2013 were retrospectively analyzed Japan hospital disinfection disinfection sterilization supply center 2500 sterile packet loss situation, put forward the cor esponding countermeasures for the cause of loss occur ed, and in 2013 October 1 ~ 28 strictly implemented. Comparing the circle of qc activity aseptic package unqualified number before and after intervention. Results October 2013 to 1 ~ 28 disinfection sterilization, 2500 aseptic package to intervene after the sterile package unqualified number by activity fel to 15.75 /weeks before 5.25 /weeks, compared with the same year 7 phases of the moon has dropped significantly, the dif erence statistical y significant ( < 0.01). Conclusion The quality control circle activities in reducing the aseptic package quantity of unqualified, the satisfactory ef ect, worthy of promotion. Al the members of the ability to solve the problem, the sense of responsibility, cohesion, motivation, communication, cooperation, pleasure, quality management technique, harmonious degree has been improved.