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致敏过程首先是抗原和IgE结合为复合物,诱致肥大细胞或嚐碱细胞释放组胺、SRSA等化学介质,再由这些化学介质导致过敏反应。中药黄芩能减少IgE的合成和分泌,抑制抗原和IgE结合,抑制化学介质释放,抑制化学介质的致敏反应,由于对致敏的各个环节都有抑制作用,在临床用于抗过敏有较好疗效,尤适用于过敏性哮喘。日本近畿大学药学部久保道德报告,利用一种甲基-甲氧基-苯乙胺与甲醛的缩聚物(称为48/80化合物)使诱导肥大细胞释放组胺,黄
Sensitization process is the first combination of antigen and IgE complex, induced mast cells or alkaline cells to release histamine, SRSA and other chemical mediators, and then by these chemical mediators cause allergic reactions. Scutellaria baicalensis diminish the synthesis and secretion of IgE, inhibit the binding of antigen and IgE, inhibit the release of chemical mediators, and inhibit the sensitization of chemical mediators. Because Scutellaria baicalensis Georgi has inhibitory effects on all aspects of sensitization, it is better in clinical use for anti-allergy Efficacy, especially for allergic asthma. Japan’s Kinki University Pharmacobiology Takubo moral report, the use of a methyl-methoxy-phenethylamine and formaldehyde condensation polymer (called 48/80 compounds) to induce mast cell release of histamine, yellow