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目的分析四川省凉山州布拖县预防艾滋病母婴传播措施的实施情况及母婴阻断效果。方法对2008年1月～2010年6月发现的177例HIV抗体阳性孕产妇的资料进行回归性分析,对其孕期服用抗病毒药物情况、妊娠结局、分娩方式、婴儿喂养方式、婴儿HIV感染情况等进行分析。结果 177例患者中,最终失访的有25例。剩余的152例中,终止妊娠的有5.9%(9/152),118例已分娩。还有25例处于妊娠期。分娩的产妇中有64.4%(76/118)服用过抗病毒药物,97.5%(115/118)为阴道分娩。已分娩的118例中,8例为死胎、死产,17例婴儿因各种原因死亡。存活的93例婴儿中,75.3%(70/93)服用了抗病毒药物,84.9%(79/93)采用人工喂养。8例婴儿在满18月龄时检测了HIV抗体,其中1例为阳性,其余为阴性。阻断率为87.5%(7/8)。结论布拖县对HIV阳性孕产妇所实施的综合干预措施对降低艾滋病母婴传播起到了良好作用,但仍需进一步加强。
Objective To analyze the implementation of mother-to-child transmission of AIDS prevention in Bu-sow County, Liangshan Prefecture, Sichuan Province, and the effect of maternal-child blockage. Methods A retrospective analysis was conducted on the data of 177 HIV-positive pregnant women who were found from January 2008 to June 2010. The incidence of antiviral drugs during pregnancy, pregnancy outcome, mode of delivery, infant feeding pattern, HIV infection in infants Analysis. Results Among the 177 patients, 25 were eventually lost to follow-up. Among the remaining 152 cases, 5.9% (9/152) terminated the pregnancy and 118 had the childbirth. There are 25 cases in pregnancy. 64.4% (76/118) of delivered mothers took antiviral drugs and 97.5% (115/118) delivered vaginal deliveries. Among the 118 cases that had been delivered, 8 were stillbirths and stillbirths, and 17 babies died due to various causes. Of 93 surviving infants, 75.3% (70/93) took antiviral drugs and 84.9% (79/93) were fed artificially. Eight infants were tested for HIV antibodies at 18 months of age, with one positive and the remaining negative. The blocking rate was 87.5% (7/8). Conclusion The comprehensive interventions of HIV / AIDS-positive pregnant women in Bu-mou County have played a good role in reducing mother-to-infant transmission of HIV / AIDS but still need to be further strengthened.