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用GnRHa-FSH-hMG-hCG方案控制性超排卵进行体外受精与胚胎移植(IVF-ET)治疗78例不孕患者,在hCG注射前抽血用放射免疫法(RIA)测孕酮(P)水平。初步了解hCG注射时血孕酮水平与IVF-ET结果的关系。结果:当P<0.35μg/L时,9例中无1例妊娠。而0.35≤P≤0.9μg/L组(54例)与P>0.9μg/L组(15例)的妊娠率分别为22.6%及26.7%。但三组间无显著差异。结论:排卵前卵泡分泌微量P可能有助于LH峰的释放,担心这种微量P的升高而提前注射hCG是没有必要的,在hCG注射前血清P<0.35μg/L妊娠率似有所下降。
In vitro fertilization and embryo transfer (IVF-ET) treatment of 78 infertile patients with controlled ovarian hyperstimulation using the GnRHa-FSH-hMG-hCG regimen was used to measure progesterone (P) by radioimmunoassay (RIA) Level. Preliminary understanding of hCG injection of blood progesterone levels and IVF-ET results. Results: When P <0.35μg / L, none of the 9 cases of pregnancy. The pregnancy rates of 0.35≤P≤0.9μg / L group (54 cases) and P> 0.9μg / L group (15 cases) were 22.6% and 26.7% respectively. However, no significant difference between the three groups. CONCLUSIONS: Pre-ovulation follicles secreting trace amounts of P may contribute to the release of LH peak. It is not necessary to pre-inject hCG with such an increase in trace P levels. Serum P <0.35 μg / L before hCG injection may have similar pregnancy rates The decline.