为了解迷路积水与耳蜗毛细胞病变的关系。作者按Kimura氏方法对15只豚鼠施行左侧内淋巴囊破坏,造成迷路积水。右耳作为对照。手术后1个月、2个月和3个月分批处死。取耳蜗用Spurr低粘度树脂包埋并依Spoendlin方法沿蜗轴平面纵形切开,解剖显微镜下见各回前庭膜出现程度不等的扩张和移位。提示迷路积水。对照耳正常。沿水平面切取各 To understand the relationship between lost water and cochlear hair cell disease. According to the Kimura’s method, 15 guinea pigs were subjected to destruction of the left endolymphatic sac causing labyrinthine hydronephrosis. Right ear as a control. One month, two months and three months after operation, they were sacrificed in batches. The cochlea were embedded with Spurr low viscosity resin and cut longitudinally along the plane of the spiral axis according to Spoendlin’s method. Under the dissecting microscope, the degree of dilatation and displacement of the vestibular membranes were observed. Tip lost water. Control ear normal. Cut along the horizontal plane