13—三体综合症(Patau syndrome)是Patau等于1980年首次报导的,它是较少见的一种综合症。据Conen和Erkman 1966年统计其频率为1/4000～1/10000。1968年Magenis等报导在13—三体综合症的患者中,女性多于男性。 13—三体综合症的最主要表型特征是唇裂(或伴有腭裂)、小眼畸形和多指(趾)畸形等多种畸形。患者一般死亡于一岁以内,偶而可活到儿童期。 Patau syndrome, first reported by Patau in 1980, is one of the less common syndromes. According to Conen and Erkman, the frequency was 1 / 4000-1 / 10000 in 1966. Magenis et al. Reported in 1968 that there were more women than men in the 13-trisomy syndrome. The main phenotypic characteristics of 13-trisomy syndrome are multiple deformities such as cleft lip (or palate), small ocular deformity and multiple digit (deformity). Patients generally die within one year of age and occasionally live to childhood.