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本文报道诊断用超声辐射人体宫内胚胎绒毛引超的脂质过氧化改变。将55名早期孕妇随机分成正常对照组(Ⅰ组)、辐射10分钟(Ⅱ组)、20分钟(Ⅲ组)、30分钟(Ⅳ组)以及超声辐射20分钟于7～10天后观察组(Ⅴ组),共五组。结果表明,常规诊断用超声连续辐射胎囊20分钟可致人体宫内绒毛细胞脂质过氧化改变(P_(Ⅰ·Ⅲ)<0.05)。丙二醛(MDA)值随超声辐射剂量增加而升高,而谷胱甘肽过氧化物酶(GSH-px)活性随超声辐射剂量增加而下降(P_(Ⅲ·Ⅳ)<0.05)。上述改变在作用7～10天后基本恢复正常(P_(Ⅲ·Ⅴ)<0.05、P_(Ⅰ·Ⅴ)>0.05),此结果提示这种损伤作用是可复性的。
This article reports the diagnosis of ultrasound-induced human uterine endometrial villus hyperlipidemia. A total of 55 early pregnant women were randomly divided into normal control group (group Ⅰ), irradiation for 10 minutes (group Ⅱ), 20 minutes (group Ⅲ), 30 minutes (group Ⅳ) and ultrasound irradiation for 20 minutes after 7 to 10 days Group), a total of five groups. The results showed that routine diagnosis of continuous intrauterine irradiation of fetal sacs with ultrasound for 20 minutes resulted in changes of lipid peroxidation in human uterine hair cells (P_ (Ⅰ · Ⅲ) <0.05). The malondialdehyde (MDA) value increased with the increase of ultrasound radiation dose, while the activity of glutathione peroxidase (GSH-px) decreased with the increase of ultrasound radiation dose (P ¢ óⅣ) <0.05). The above changes were basically normal after 7 to 10 days (P_ (Ⅲ Ⅴ) <0.05, P_ (Ⅰ Ⅴ)> 0.05). These results suggest that this injury is regressible.