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目的探讨皮病性淋巴结炎(DL)的临床病理及18F-FDG PET/CT表现特点,提高对本病的诊断水平。方法搜集本院2例病理确诊为DL的患者资料,并检索国内外近10年关于DL的文献,回顾性分析DL的临床病理及PET/CT表现特点。结果 2例患者临床均表现为反复发热,全身浅表淋巴结肿大,皮肤瘙痒伴红斑,骨髓增生活跃。PET/CT检查发现2例患者全身多处淋巴结肿大伴糖代谢增高,SUVmax>2.5,摄取18FDG最高的部位在腋窝,SUVmax达12,同时均伴有脾肿大伴糖代谢增高,骨髓浓聚增高。结论 DL患者在PET/CT上多表现为全身多处淋巴结肿大伴18FDG摄取增高,腋窝、腹股沟、颈部多见,呈对称性分布,无融合趋势。DL的主要临床表现为全身多发无痛性淋巴结肿大,常伴有皮肤改变。病理为非特异性淋巴结反应性增生。
Objective To investigate the clinical and pathological features of dermatitic lymphadenitis (DL) and the features of 18F-FDG PET / CT and to improve the diagnosis of this disease. Methods The data of 2 patients with pathologically diagnosed DL in our hospital were collected. The literature about DL at home and abroad was retrieved and the clinical pathology and PET / CT features of DL were retrospectively analyzed. Results The clinical manifestations of 2 patients were both recurrent fever, generalized superficial lymph nodes, pruritus with erythema and active bone marrow hyperplasia. PET / CT examination found that two patients with systemic lymphadenopathy with increased sugar metabolism, SUVmax> 2.5, the highest intake of 18FDG in the armpit, SUVmax 12, accompanied by splenomegaly accompanied by increased glucose metabolism, bone marrow enrichment. Conclusions The multidimensional lymphadenectasis in patients with DL on PET / CT is associated with increased 18FDG uptake. The armpits, groin and neck are more common in DL patients, showing a symmetrical distribution with no tendency of fusion. The main clinical manifestations of DL are multiple systemic painless lymphadenopathy, often accompanied by skin changes. Pathology of non-specific lymph node reactive hyperplasia.