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目的研究腹腔镜手术联合诺雷德治疗重度卵巢型内异症的临床疗效。方法选择008年6月-2010年6月间我院接诊的102例重度卵巢型内异症患者,随机分为实验组和对照组各51例。实验组经腹腔镜手术后,采用诺雷德进行联合治疗;对照组腹腔镜手术后采用孕三烯酮进行辅助治疗。治疗后,对两组患者进行为期2年的随访,记录并比较两组患治疗后的有效率、复发率和合并不孕症患者的妊娠率。结果术后,实验组有效率(82.4%)明显高于对照组(60.8%),复发率(9.8%)明显低于对照组(33.3%),术后1年,实验组不孕症患者的妊娠率(47.6%)明显高于对照组(33.3%),差异有统计学意义(P<0.05)。结论腹腔镜手术联合诺雷德治疗重度卵巢型内异症的临床疗效显著,可降低病情复发率,提高不孕症患者治疗后的妊娠率,值得临床推广应用。
Objective To study the clinical efficacy of laparoscopic surgery combined with Nuodeide in the treatment of severe ovarian endometriosis. Methods A total of 102 patients with severe ovarian endometriosis admitted from June 008 to June 2010 in our hospital were randomly divided into experimental group and control group with 51 cases each. After the laparoscopic surgery in the experimental group, Noread was used for combination therapy; in the control group, gestrinone was used for adjuvant therapy after laparoscopic surgery. After treatment, two groups of patients were followed up for 2 years, record and compare the two groups of patients after treatment efficiency, recurrence rate and pregnancy rate in patients with infertility. Results After operation, the effective rate of experimental group (82.4%) was significantly higher than that of control group (60.8%), and the recurrence rate (9.8%) was significantly lower than that of control group (33.3% The pregnancy rate (47.6%) was significantly higher than that of the control group (33.3%), the difference was statistically significant (P <0.05). Conclusion Laparoscopic surgery combined with Nuodeide treatment of severe ovarian endometriosis significant clinical efficacy, can reduce the recurrence rate, improve the pregnancy rate of infertility patients after treatment, it is worthy of clinical application.