自从1965年在意大利Perugia召开的“动物肺癌会议”上提出寻找适当的诱癌方法以来,不少学者对诱发动物肺癌的方法学进行了大量的研究工作。至目前为止,文献中报导的许多方法中,以Saffiotti等和Schreiber等的气管内灌注致癌质水悬液法比较近似于人类肺癌发生的条件,为一些研 Since the “Lung Cancer Conference of the Animals” held in Perugia, Italy, in 1965, it has been proposed to search for appropriate methods to induce cancer. Many scholars have conducted a lot of research on the methodologies that induce animal lung cancer. To date, many methods reported in the literature have compared the conditions of human lung cancer with Saffiotti et al. and Schreiber et al.’s intratracheal infusion of carcinogenic aqueous suspensions.