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我院自1684年4月～1985年6月用乙胺碘呋酮治疗阵发性房颤25例,现分析报导如下。临床资料一、病例选择:本组25例均为门诊病例,经心电图或动态心电图监测确诊为阵发性房颤。病程均在半年以上,最长者11年。发作频度,最少每周2次,多者每日发作2～10余次。每次持续时间10分至36小时,且有自觉症状,影响正常生活与工作。本组中,男22例,女3例。年龄25～65岁。临床诊断冠心病12例,高血压2例,二尖瓣脱垂4例,原因不明7例。二、方法:本组均经过病史、体检、血尿便常规、肝肾功能、T_3T_4、胸片、超声心动图等检查,确诊后停用一切其它抗心律失常药一周。开始服药后每周门诊复查血压、心率、心律、ECG 观察 Q-Tc 等每月裂隙灯查角膜碘微粒沉着情况,每三个月复查 T_3T_4一次。
Our hospital from April 1684 to June 1985 with amiodarone treatment of 25 cases of paroxysmal atrial fibrillation, are analyzed and reported as follows. Clinical data First, the case selection: 25 cases of this group are outpatient cases, diagnosed by ECG or Holter monitoring of paroxysmal atrial fibrillation. Duration of more than six months, the longest 11 years. The frequency of attacks, at least 2 times per week, more than 2 to 10 episodes per day. Each duration of 10 minutes to 36 hours, and symptoms, affecting normal life and work. In this group, 22 males and 3 females. Aged 25 to 65 years old. Clinical diagnosis of coronary heart disease in 12 cases, 2 cases of hypertension, mitral valve prolapse in 4 cases, unexplained 7 cases. Second, the method: This group were medical history, physical examination, routine hematuria, liver and kidney function, T_3T_4, chest X-ray, echocardiography and other tests, diagnosis and disable all other antiarrhythmic drugs a week. Blood pressure, heart rate, heart rate, ECG observation Q-Tc and other monthly slit lamp examination of corneal iodine microparticle deposition after starting medication weekly review, T_3T_4 once every three months.