用豚鼠巨噬细胞试验,检查人的淋巴细胞在对抗原反应中所产生的巨噬细胞游走抑制因子(MIF),证明在研究细胞超敏感反应上是一种有用的方法。本研究证明80名患有不同癌肿的病人中,21名的淋巴细胞在对自身肿瘤抽出物反应中产生MIF。同时还用自身组织作为正常抗原的对照。此外,在这些病人中 MIF 产生的相对频率随疾病进展成反比例的变化。例如,连续研究结果表明,通过游走抑制试验 Using guinea pig macrophage assays to examine human macrophage migration inhibitory factor (MIF) produced by human lymphocytes in response to the antigen, it is demonstrated to be a useful method for studying cellular hypersensitivity reactions. This study demonstrated that 21 out of 80 patients with different cancers developed MIF in response to their own tumor extracts. At the same time also use their own tissue as a control of normal antigens. In addition, the relative frequency of MIF production in these patients varies inversely with disease progression. For example, continuous studies have shown that inhibition is tested by wandering