目的总结川崎病(KD)临床特点,探讨冠状动脉损害(CAL)的高危因素。方法对178例KD患者的临床资料进行回顾性分析,总结其临床特点;将KD患者分为冠脉损害组(CAL)和无冠脉损害组(NCAL),比较两组的临床表现及实验室结果。结果川崎病男性患者多见,发病高峰在4~6月份;CAL组较NCAL组:其年龄、热程、血红蛋白、血小板差异有统计学意义。结论早期症状不典型病例,CAL的发生率较高,应引起重视。 Objective To summarize the clinical features of Kawasaki disease (KD) and investigate the risk factors of coronary artery lesion (CAL). Methods Clinical data of 178 patients with KD were analyzed retrospectively to summarize their clinical features. Patients with KD were divided into coronary artery injury group (CAL) and non-coronary artery injury group (NCAL). The clinical manifestations and laboratory performance of the two groups were compared result. Results Kawasaki disease was more common in males and the peak incidence was from April to June. The CAL group had statistically significant differences compared with NCAL group in age, thermal history, hemoglobin and platelet count. Conclusions The early symptoms of atypical cases, the higher the incidence of CAL, should pay attention.