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目的了解维吾尔族、汉族孕妇妊娠期亚临床甲状腺功能减退症的妊娠期并发症及分娩结局情况,为减少维吾尔族、汉族孕妇亚临床甲状腺功能减退症的发生,提高出生人口素质提供理论依据。方法采用问卷法对2014年01月至2014年12月就诊于乌鲁木齐市妇幼保健院符合本研究纳入标准的维吾尔族、汉族孕妇进行面对面的调查,收集并分析维吾尔族、汉族妊娠期亚临床甲状腺功能减退症患者的体格检查、实验室检测等相关指标,观察SCH患者是否发生不良妊娠期合并症、SCH的分娩结局情况,并用统计学方法进行分析。结果 1.3280名汉族孕妇中,妊娠期亚临床甲状腺功能减退症的检出率为12.38%;3428名维吾尔族中,妊娠期亚临床甲状腺功能减退症的患者检出率为14.29%。2.与非亚临床甲状腺功能减退症群组对比,合并亚临床甲状腺功能减退的汉族、维吾尔族孕妇妊娠期糖尿病、贫血的发生率均增高(P<0.05)。汉族、维吾尔族亚临床甲状腺功能减退症的产妇流产、早产及剖宫产的几率均明显增高(P<0.05)。结论新疆地区妊娠期亚临床甲状腺的发病情况令人担忧,妊娠期亚临床甲状腺功能减退症造成特定的妊娠期合并症及不良出生结局增加,应加强孕前、孕期的健康宣教,积极开展常见疾病监测及诊治,减少相应的妊娠期并发症,以提高出生人口素质。
Objective To understand the pregnancy complications and delivery outcomes of subclinical hypothyroidism in pregnant women of Uygur and Han nationality, and to provide theoretical basis for reducing subclinical hypothyroidism and enhancing the quality of birth population of Uygur and Han pregnant women. Methods A questionnaire was used to investigate the Uyghur and Han pregnant women attending Urumqi MCH hospital in Urumqi from January 2014 to December 2014 in a face-to-face manner. The clinical data of subclinical thyroid function in Uygur and Han Chinese during pregnancy were collected and analyzed. Hypothyroidism patients physical examination, laboratory tests and other related indicators to observe whether SCH patients with adverse pregnancy complications, SCH delivery outcomes, and statistical methods for analysis. Results 1.3280 Han pregnant women, the detection rate of subclinical hypothyroidism during pregnancy was 12.38%; 3428 Uygur, the detection rate of subclinical hypothyroidism during pregnancy was 14.29%. Compared with non-subclinical hypothyroidism group, Han and Uygur pregnant women with subclinical hypothyroidism had higher incidence of gestational diabetes mellitus and anemia (P <0.05). Han, Uighur subclinical hypothyroidism, abortion, premature delivery and cesarean section were significantly increased (P <0.05). Conclusions The prevalence of subclinical thyroid during pregnancy in Xinjiang is alarming. Subclinical hypothyroidism in pregnancy causes specific complications during pregnancy and increased unfavorable birth outcomes. Health education should be strengthened before pregnancy and during pregnancy, and frequent monitoring of common diseases should be carried out And diagnosis and treatment, reduce the corresponding complications during pregnancy, in order to improve the quality of the birth population.