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Left atrial appendage occlusion (LAAO) has been widely accepted as an altative to oral anticoagulation for stroke prevention in patients with nonvalvular atrial fibrillation (AF).However,the periprocedural complications such as device embolization are still challenging.[1] Here,we reported a rare case of an AMPLATZERTM Cardiac Plug (ACP;St.Jude Medical,USA) device disconnection with the delivery cable during the LAAO procedure.