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胃肠道类癌少见,约占尸检数的1.2%,其中位于阑尾者居多(48%),其次为直肠(17%)和回肠(12%),其生物学特性已被充分阐明,故对这些部位类癌的治疗很少有分歧意见。凡孤立性肿瘤超过2cm大小者均有明显转移倾向,应整块切除原生肿瘤及其引流的淋巴组织。相反,胃类癌虽仅占整个胃肠道类癌约2%,更为少见,但对其生物学行为的了解不多,其临床和病理表现多变,且常伴有自身免疫性和内分泌病变,如糖尿病、甲状腺功能低下、阿狄森病、恶性贫血以及A型慢性萎缩性胃炎等,且与高胃泌素血症密切相关。作者
Gastrointestinal carcinoids are rare and account for about 1.2% of autopsies, among which the majority are appendix (48%), followed by the rectum (17%) and ileum (12%). Their biological characteristics have been fully elucidated. There is little disagreement about the treatment of carcinoids in these areas. All solitary tumors larger than 2 cm in size have a tendency to metastasize, and primary tumors and their draining lymphoid tissues should be removed in a lump. On the contrary, gastric carcinoids, although accounting for only about 2% of the entire gastrointestinal carcinoid, are less common, but little understanding of their biological behavior, clinical and pathological changes, and often accompanied by autoimmune and endocrine Lesions, such as diabetes, hypothyroidism, Addison’s disease, pernicious anemia, and type A chronic atrophic gastritis, and are closely related to hypergastrinemia. The author