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以酸性氧化铝为吸附剂,制备了一个118MBq的188W-188Re发生器,并对发生器性能进行了为期4个月的检测。结果表明,188Re的淋洗产额在80%—90%之间,188W的穿透率约为1.0×10-4%。由于采用了较大高径比的交换柱,使188Re的放射性比活度较高,能满足用于放射免疫治疗研究的抗肿瘤单克隆抗体标记的要求。
A 188 MBq 188W-188Re generator was prepared using acidic alumina as adsorbent, and the generator performance was tested for 4 months. The results showed that the elution yield of 188Re was between 80% -90% and that of 188W was about 1.0 × 10-4%. Due to the adoption of the exchange column with larger aspect ratio, the specific activity of 188Re is higher, which can meet the requirement of anti-tumor monoclonal antibody labeling for radioimmunotherapy research.