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目的:探讨无导线起搏器在临床应用中的可行性及短期安全性。方法:研究自2019年12月到2020年9月前瞻性入选36例在云南省第一人民医院植入无导线起搏器的患者，均符合指南推荐Ⅰ类或Ⅱ类VVIR起搏适应证。通过观察起搏参数及症状改善的情况评估其有效性，观察术中及术后3个月内并发症的发生情况，评估其短期安全性。结果:36例患者均完成无导线起搏器植入，成功率100%。其中男25例（69%，25/36），年龄（73±14）岁，年龄范围15~87岁，随访（6±3）个月。其中病态窦房结综合征患者8例，心房颤动合并长RR间期12例，二度Ⅱ型、三度房室传导阻滞16例。术中起搏阈值为（0.46±0.21）V/0.24 ms，感知为（10.8±4.5）mV，阻抗为（871±268）Ω，术后随访3个月感知及阈值均平稳，阻抗在3个月的随访中较术中明显下降[（813±197）Ω对（689±149）Ω，n P=0.01]。术后24 h血管彩超检查发现股静脉穿刺点处静脉血栓11例（11/36，31%），抗凝治疗1个月后复查血栓均消失，未出现肺栓塞等严重后果。未发现穿刺部位血肿、假性动脉瘤、动静脉瘘的血管并发症。1例患者术后24 h出现阈值升高，术后1个月阈值恢复正常。n 结论:无导线起搏器植入操作简便、成功率高、短期安全性好，但其远期安全性和有效性仍有待进一步研究。“,”Objective:To explore the utility and short-term safety of leadless transcatheter pacemaker (LTP) .Methods:From December 2019 to September 2020, we prospectively analyzed 36 patients with LTP implantation in The First People′s Hospital of Yunnan Province. All patients met the indications of VVIR pacing of class Ⅰ or Ⅱ recommended by the guideline. The effecacy was evaluated by observing the improvement of pacing parameters and symptoms, and the short-term safety was evaluated by observing the occurrence of intraoperative and postoperative complications within 3 months.Results:A total of 36 patients completed LTP implantation.The success rate was 100%. Among them, 25 (69%, 25/36) patients were males with an average age of (73±14) years (15-87 years) . The average follow-up time was (6±3) months. Among them, 8 patients with sick sinus syndrome, and 12 patients with atrial fibrillation and long RR interval, and 16 patients with MobitzⅡ or high degree atrioventricular block. The average pacing threshold was (0.46±0.21) V/0.24 ms, the average sense was (10.8±4.5) mV, and the average impedance was (871±268) Ω. The sense and pacing threshold were stable during 3 months of follow-up n . The impedance at months after procedure was decreased significantly [ (813±197) Ω vs. (689±149) Ω, n P=0.01] . In 11 cases (11/36, 31%) , venous thrombosis was found at the puncture point of femoral vein by color Doppler ultrasound. After one month of anticoagulant treatment, the thrombosis disappeared, and no serious consequences such as pulmonary embolism occurred. There were not hematoma, pseudoaneurysm, arteriovenous fistula and other vascular complications. The pacing threshold increased in 1 case and returned to normal after one month.n Conclusion:LTP implantation performed in our study archived a high implant success rate with a favorable safety profile. The longterm safety and benefit of LTP need to be evaluated in future clinical studies.