论文部分内容阅读
目的了解武鸣县疑似预防接种异常反应(AEFI)的发生特征,评价疫苗的安全性,改善预防接种服务质量。方法采用描述性分析方法对武鸣县发生的AEFI进行流行病学分析。结果武鸣县在2008-2012年共报告AEFI病例76例,累计发生率为6.61/10万,男性多于女性,<1岁儿童占47.36%。AEFI报告发生率居前3位的疫苗是两个不同公司生产的23价肺炎球菌多糖疫苗和卡介苗,其中一般反应占38.16%、异常反应占47.37%、心因性反应占3.95%。治愈病例占90.79%,好转病例占9.21%。AEFI监测系统及时报告率97.37%,个案报告完整率100.00%。结论疫苗自身安全性良好,全县AEFI疫情上报及时、完整,监测体系走上正轨,今后应继续加强预防接种人员在发生AEFI后合理解释、规范处置等方面的培训,提高预防接种服务质量。
Objective To understand the occurrence characteristics of suspected AEFI in Wuming County, evaluate the safety of vaccines and improve the quality of vaccination services. Methods Descriptive analysis was used to analyze the epidemiology of AEFI in Wuming County. Results A total of 76 cases of AEFI were reported in Wuming County from 2008 to 2012, with a cumulative incidence of 6.61 / 100,000, more men than women, and 47.36% of children <1 year old. The top 3 vaccines for AEFI reporting were the 23-valent pneumococcal polysaccharide vaccine and BCG vaccine produced by two different companies, of which 38.16% were normal, 47.37% were abnormal, and 3.95% were cardiorespiratory. Cure cases accounted for 90.79%, improved cases accounted for 9.21%. AEFI monitoring system timely reporting rate of 97.37%, case report complete rate of 100.00%. Conclusion The vaccines have good self-safety. The timely, complete and timely reporting of AEFI epidemics throughout the county is on the right track. In the future, vaccination personnel should continue to strengthen their training on such issues as rational interpretation and standardization after AEFI, and improve the quality of vaccination services.