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目的:探讨如何改善静脉注射前列地尔引起注射部位的局部反应。方法选取我院2013年1月~2013年12月使用前列地尔患者40例,随机分成两组A组和B组,每组20人。A组采用5ug的前列地尔注射液静脉注射,B组采用5ug的前列地尔注射液静脉注射加入10mL生理盐水或葡萄糖。观察其局部反应。结果 A组出现不良反应明显多于B组。结论前列地尔注射液加入10mL生理盐水或葡萄糖,可缓解直接注射引起的不良反应,值得在临床推广。“,”objective to explore how to improve intravenous forefront, cause local reactions at the injection site. Methods select our hospital from January 2013 to December 2013, use among 40 cases of patients, randomly into two groups: group A and group B, 20 people in each group. The forefront of the group A with 5 ug to injection intravenous injection, the forefront of the group B with 5 ug, add 10 ml saline or glucose injection intravenous infusion. The local reaction was observed. Results in group A bad reaction significantly more than group B. Conclusion lead to add 10 ml saline or of injection, can relieve the adverse reactions caused by direct injection, is worth popularizing in clinical.