治疗高血压时多剂并用的机会多,诊治时间长,因此药物的相互作用和副作用成为重要问题。从药动学和药理学看药物的相互作用在吸收阶段,如高脂血症时使用的降血脂药消胆胺,由于在肠腔内吸收包括降压药在内的多种物质,而使噻嗪类利尿药的吸收减少。如在使用嗪噻类利尿剂前后2h内给予消胆胺8g,约60％的利尿药吸收不良。在分布阶段, Treatment of hypertension and more opportunities to use multiple, diagnosis and treatment of a long time, so drug interactions and side effects become an important issue. Pharmacokinetics and pharmacology to see the interaction of drugs In the absorption stage, such as hyperlipidemia when using hypocholesterolemic cholestyramine, due to absorption in the intestine, including antihypertensive drugs, including a variety of substances, and Thiazide diuretics decreased absorption. Such as the use of urethrazine thiazide diuretic within 2h before cholestyramine given 8g, about 60% of diuretic malabsorption. In the distribution stage,