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作者测定了241例早期新生儿和33例成人的血清钙(Ca)、磷(PHOS)、碱性磷酸酶(ALP),并分析了各指标的相互关系.结果显示:早期新生儿和成人血清Ca分别为2.50±0.29mmol/L、2.54±0.30mmol/L(P>0.05);早期新生儿男女血清Phos分别为1.82±0.53mmol/L、1.95±0.53mmol/L(P<0.01),成人血清Phos为1.14±0.15mmol/L(P<0.01);早期新生儿和成人血清ALP分别为95.6±32.1 IU/L、54.7±13.8 IU/L(P<0.01)。早期新生儿血清Ca与PHOS相关(P<0.05);血清ALP与Ca和PHOS无关(P>0.05).早期新生儿血清ALP与孕周和日龄呈负相关(P<0.050).结果表明:早期新生儿血清Ca和PHOS浓度不受ALP活性变化的影响;早期新生儿可以依靠从母体和自身来源的Ca、PHOS来维持血中Ca与PHOS的暂时平衡,然而生后必须及时补充外源性Ca和PHOS。
The authors measured the serum calcium (Ca), phosphorus (PHOS) and alkaline phosphatase (ALP) in 241 early neonates and 33 adults and analyzed the relationship between the indicators.The results showed that: early neonatal and adult serum Ca 2+ were 2.50 ± 0.29mmol / L and 2.54 ± 0.30mmol / L respectively (P> 0.05). The serum Phos of males and females in early neonates were 1.82 ± 0.53mmol / L and 1.95 ± 0.53mmol / L, respectively Serum Phos was 1.14 ± 0.15mmol / L (P <0.01). Serum ALP in early neonates and adults were 95.6 ± 32.1 IU / L and 54.7 ± 13.8 IU / L, respectively (P <0.01). Serum Ca of early neonates was correlated with PHOS (P <0.05), serum ALP had no correlation with Ca and PHOS (P> 0.05) .The ALP of early neonates was negatively correlated with gestational age and age (P <0.05) .The results showed that: Early neonatal serum concentrations of Ca and PHOS are not affected by changes in ALP activity; early neonates can rely on calcium and PHOS from the maternal and self-derived sources to maintain a temporary balance of Ca and PHOS in the blood, but after birth must be replenished exogenously Ca and PHOS.