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目的:探讨氨甲蝶呤与2种不同剂量米非司酮联合治疗未破裂型异位妊娠的疗效。方法:收治未破裂型异位妊娠患者114例,随机分为两组,A组氨甲蝶呤单次肌肉注射,剂量50mg/m2,同时给米非司酮50mg口服,每12小时1次,连服6天,总量600mg。B组氨甲蝶呤单次肌肉注射,剂量50mg/m2,同时给米非司酮200mg顿服,总量200mg。结果:两组治疗效果的统计学检验结果,P>0.05,说明两组治疗效果没有差别。结论:氨甲蝶呤联合米非司酮治疗异位妊娠时,每疗程米非司酮总量200mg组与每疗程米非司酮总量600mg组,治疗效果相当。
Objective: To investigate the efficacy of methotrexate combined with two different doses of mifepristone in the treatment of unruptured ectopic pregnancy. Methods: One hundred and fourteen patients with unruptured ectopic pregnancy were randomly divided into two groups. Group A received a single intramuscular injection of methotrexate at a dose of 50 mg / m2 and given mifepristone 50 mg orally once every 12 hours. Even for 6 days, the total 600mg. B group methotrexate intramuscular injection of a single dose of 50mg / m2, while giving mifepristone 200mg Dayton clothing, the total 200mg. Results: The results of statistical analysis of two groups of treatment effect, P> 0.05, indicating no difference between the two groups. CONCLUSION: When methotrexate combined with mifepristone for ectopic pregnancy, the total effective dose of mifepristone is 200 mg per course of treatment and 600 mg of mifepristone per course of treatment is equivalent.