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心血管系统疾病是严重危害人民生命和健康的常见病、多发病,是许多国家人口死亡的首位原因。据我国首次人口死亡原因的统计研究结果显示,心血管疾病居第一位,脑血管疾病居第二位。因此,开发研究疗效确切、副作用小和使用方便的心血管疾病的防治药物仍是当今药物研制中的首要课题之一。1988年世界销量最大的仍然是心血管药物,在1987～1990年四年间,首次在世界范围内上市的心血管药物(包括部分血液系统药物)有57种,其中1987年14种,1988年20种,1989年12种和1990年11种,分别占当年
Cardiovascular diseases are common diseases and frequently-occurring diseases that seriously endanger people’s life and health and are the leading cause of death in many countries. According to the statistical analysis of the causes of death of the first population in China, cardiovascular disease ranks first and cerebrovascular disease ranks second. Therefore, it is still one of the most important topics in the current drug development to develop and control the cardiovascular disease prevention and treatment with definite curative effect, small side effects and easy to use. In 1988, the world’s largest-ever sales volume was still cardiovascular drugs. For the first time in four years from 1987 to 1990, there were 57 cardiovascular drugs (including some blood-system drugs) listed in the world, including 14 in 1987 and 20 in 1988 Species, 12 species in 1989 and 11 species in 1990, respectively, the year