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目的 探讨银质针导热疗法联合臭氧、玻璃酸钠关节腔注射治疗原发性膝关节骨性关节炎的临床疗效.方法 将150例原发性膝骨关节炎患者按随机数字表法分为3组,A组采用银质针+玻璃酸钠膝关节腔注射治疗,B组采用银质针+臭氧膝关节腔注射治疗,C组采用银质针+玻璃酸钠+臭氧膝关节腔注射治疗,总疗程5周.采用视觉模拟量表和西安大略和麦克马斯特大学骨关节炎调查表评定患者疼痛情况及临床疗效. 结果 治疗后24 h起B组及C组视觉模拟量表评分均较治疗前显著持续降低(P<0.05),治疗后1个月末A组评分较治疗前显著降低(P<0.05).治疗后C组不同时间点视觉模拟量表评分均显著低于A组与B组(P<0.05).治疗后1个月末,3组西安大略和麦克马斯特大学骨关节炎调查表各项评分均显著低于治疗前(P<0.01),且C组各项评分均显著低于A组、B组(P<0.01).结论 银质针联合臭氧、玻璃酸钠治疗原发性膝关节骨性关节炎疗效确切,可显著减轻患者膝关节疼痛,改善患膝关节功能,无感染、过敏等严重不良反应,是一种安全有效的治疗方法.“,”Objective To explore the efficacy of silver needle thermal conduction therapy combined with ozone and hyaluronate sodium injection of articular cavity in primary knee osteoarthrosis (PKO).Methods A total of 150 PKO patients were randomly divided into 3 groups, group A was treated with silver needle + intra-articular injections of hyaluronate sodium, B with silver needle + intra-articular injections of ozone, C with silver needle + intra-articular injections of ozone and hyaluronate sodium, and total course of treatment was 5 weeks.Pain status and efficacies were assessed with the Visual analogue scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).Results Since the 24 hour after treatment the VAS scores of group B and C significantly continuously lowered (P<0.05) and so did that in A at the end of 1 month treatment (P<0.05).The VAS scores at all time points after treatment were significantly lower in group C than in A and B (P<0.05).At the end of 1 month treatment the WOMAC scores of the 3 groups lowered more significantly compare with pre treatment (P<0.01) and were significantly lower in group C than in A and B (P<0.01).Conclusion Silver needle+ ozone and hyaluronate sodium have a certain efficacy in the PKO, could notably lighten pain, improve knee joint function, have no severe adverse reactions of infection and allergy and so on, and are a safe and effective therapeutic method.