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目的了解北京市通州区监测点乙型病毒性肝炎(乙肝)诊断、报告中存在的问题,为乙肝防治提供依据。方法对监测点符合病例定义的乙肝病例进行调查和采血,复核抗甲型肝炎病毒抗体IgM(抗-HAV IgM)、乙肝病毒表面抗原(HBsAg)和乙肝病毒核心抗体IgM(抗-HBc IgM),最终进行实验室诊断。结果对符合乙肝监测病例定义的133例病例进行分析,急性乙肝疑似病例占27.07%,急性乙肝确诊病例占5.26%,慢性乙肝疑似病例占8.27%,慢性乙肝确诊病例占29.32%,乙肝后肝硬化占17.29%,原发性肝细胞癌占12.78%。对108例进行实验室复核,复核后急性乙肝确诊病例占19.44%,慢性乙肝确诊病例占32.41%。急性乙肝疑似病例复核后构成变化最大。结论通州区目前报告的乙肝病例中以慢性病例为主,从监测点估算通州区急性乙肝发病率要低于疫情报告网的发病率,慢性乙肝发病率要高于疫情报告网的发病率。
Objective To understand the diagnosis and report of hepatitis B in Tongzhou district of Beijing, and to provide evidences for the prevention and treatment of hepatitis B. Methods The hepatitis B cases with the defined cases were investigated and blood samples were collected. The anti-hepatitis A virus IgM (anti-HAV IgM), hepatitis B virus surface antigen (HBsAg) and hepatitis B virus core antibody IgM (anti-HBc IgM) Final laboratory diagnosis. Results A total of 133 cases were identified according to the definition of hepatitis B surveillance. The number of suspected cases of acute hepatitis B was 27.07%, the incidence of acute hepatitis B was 5.26%, the proportion of suspected cases of chronic hepatitis B was 8.27%, the incidence of chronic hepatitis B was 29.32% Accounting for 17.29%, primary hepatocellular carcinoma accounted for 12.78%. 108 cases of laboratory review, review confirmed 19.44% of acute hepatitis B cases, chronic hepatitis B confirmed cases accounted for 32.41%. After the review of suspected cases of acute hepatitis B changes in the composition of the largest. Conclusion The chronic hepatitis B cases reported in Tongzhou District are mainly chronic. The incidence of acute hepatitis B in Tongzhou District is lower than that of epidemic reporting network. The incidence of chronic hepatitis B is higher than that of epidemic reporting network.