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目的探讨腹腔镜前列腺癌根治术患者术后并发症及疗效。方法选取2013年1月至2015年11月间辽宁省葫芦岛市中心医院收治的行前列腺癌根治术的80例前列腺癌患者,采用随机数表法分为观察组与对照组,每组40例,观察组患者采用腹腔镜前列腺癌根治术,对照组患者采用开放式前列腺癌根治术。比较两组患者术中出血量、尿管拔除时间、住院时间、术后并发症和1年内的生化复发率及完全控尿率。结果观察组患者术中出血量、尿管拔除时间和住院时间分别为(762.5±125.3)ml、(14.2±3.7)d和(15.3±4.7)d,均低于对照组患者的(1346.7±164.2)ml、(19.2±4.3)d和(23.4±6.1)d,差异均有统计学意义(均P<0.05)。观察组患者并发症发生率为15.0%,分别为吻合口狭窄1例、尿漏2例和勃起功能障碍3例,对照组患者的并发症发生率为35.0%,分别为吻合口狭窄3例、尿漏5例和勃起功能障碍6例,两组组间比较,差异有统计学意义(P<0.05)。观察组患者生化复发率为2.5%低于对照组患者的15.0%,观察组患者完全控尿率为72.5%高于对照组患者的52.5%,两组组间比较,差异均有统计学意义(均P<0.05)。结论腹腔镜前列腺癌根治术能够明显降低患者术后并发症发生率,有利于患者术后康复。
Objective To investigate the postoperative complications and efficacy of laparoscopic radical prostatectomy. Methods Eighty prostate cancer patients underwent radical prostatectomy from January 2013 to November 2015 in Huludao Central Hospital of Liaoning Province were randomly divided into observation group and control group with 40 cases in each group The patients in the observation group were treated with laparoscopic radical prostatectomy and the control group were treated with open prostatectomy. The blood loss, catheter removal time, hospital stay, postoperative complications, biochemical recurrence rate and complete control of urine in one year were compared between the two groups. Results The intraoperative blood loss, catheter removal time and hospital stay in the observation group were (762.5 ± 125.3) ml, (14.2 ± 3.7) days and (15.3 ± 4.7) days, respectively, which were lower than those in the control group (1346.7 ± 164.2 ) ml, (19.2 ± 4.3) d and (23.4 ± 6.1) d, respectively. There were significant differences between the two groups (all P <0.05). The incidence of complication in the observation group was 15.0%, 1 case was anastomotic stenosis, 2 cases urinary leakage and 3 cases erectile dysfunction. The incidence of complications in the control group was 35.0%, 3 cases were anastomotic stenosis, 5 cases of urinary leakage and 6 cases of erectile dysfunction. The difference between the two groups was statistically significant (P <0.05). The rate of biochemical recurrence in the observation group was 2.5% lower than that in the control group (15.0%). The total control urine volume in the observation group was 72.5% higher than that in the control group (52.5%). There was significant difference between the two groups All P <0.05). Conclusion Laparoscopic radical prostatectomy can significantly reduce the incidence of postoperative complications in patients with postoperative recovery.