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目的:探讨胰岛细胞瘤精准切除术的临床应用价值。方法:对2005年1月—2012年7月收治的24例行胰岛细胞瘤精准切除患者的临床资料进行回顾性分析。结果:24例患者均采取精准切除术,即最小创伤,并尽可能保留有功能的胰腺组织;全组手术时间1.5~4.8(2.8±0.7)h,术中出血量50~500(213.78±46.60)mL,术后住院时间12~32(13.5±6.17)d;术后发生胰瘘4例,均经保守治疗痊愈;所有患者均痊愈出院。术后随访4个月至7年,患者无死亡、恶变或复发等情况,生活质量均良好。结论:对单发的良性胰岛细胞瘤的手术治疗,建议采取结合胰腺组织学特性的胰岛细胞瘤精准切除术。
Objective: To investigate the clinical value of precise excision of islet cell tumor. Methods: A retrospective analysis was performed on the clinical data of 24 patients with pancreatic islet cell tumor who were admitted to our hospital from January 2005 to July 2012. Results: Twenty-four patients underwent exact excision, minimal trauma and preserved functional pancreatic tissue. The operative time was 1.5-4.8 (2.8 ± 0.7) h and the intraoperative blood loss was 50-500 (213.78 ± 46.60) ) mL, postoperative hospital stay 12 to 32 (13.5 ± 6.17) d; 4 cases of pancreatic fistula occurred after surgery, were cured by conservative treatment; all patients were cured and discharged. The patients were followed up for 4 months to 7 years without any death, malignancy or recurrence, and the quality of life was good. Conclusion: For the treatment of benign pancreatic islet cell tumor, it is recommended to take the accurate excision of pancreatic islet cell tumor combined with histological features of the pancreas.