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最近,我们在对某些药物的含量测定时,发现同一批检品用不同厂家的试剂检验,测定的结果差别很大,现举例说明如下。1 醋酸泼尼松片的含量测定。该药为江西国药有限责任公司生产,批号为990722,规格5mg/片。先用安徽蚌埠华星精细化工厂生产的无水乙醇(分析纯)按中国药典1995年二部第1082页的方法稀释,使用上海分析仪器厂生产的7520型分光光度计依法测得其含量为标承量的90.0％;后改用安徽淮南化学试剂厂生产的无水乙醇(分析纯)按同法平行操作,其含量为标示量的96.0％。2 维生素B_6注射液的含量测定。该药为芜湖长江药业有限公司生产,批号为990819-1,规格为50mg/ml。先用江苏宜兴芳桥建筑保湿化工厂生产的盐酸(分析纯)按中国药典
Recently, we in the determination of the content of some drugs, found that the same batch of seized goods with different manufacturers reagent test, the results measured vary widely, are as follows. 1 prednisone acetate tablets content determination. The drug for the Jiangxi Pharmaceutical Co., Ltd. production, batch number 990722, specifications 5mg / piece. The first use of Anhui Bengbu Huaxing Fine Chemical Plant production of ethanol (analytical grade) according to the Chinese Pharmacopoeia 1995 two 1082th page of the method of dilution, the use of Shanghai Analytical Instrument Factory 7520 spectrophotometer measured according to the law as the standard 90.0% of the capacity; after the switch to Anhui Huainan chemical reagent plant production of anhydrous ethanol (analytical grade) according to the same method of parallel operation, the content of 96.0% of the labeled amount. 2 vitamin B_6 injection content determination. The drug for the Wuhu Yangtze Pharmaceutical Co., Ltd. production, batch number 990819-1, specifications for 50mg / ml. Hydrochloric acid (Analytical Pure) manufactured by Jiangsu Yixing Fangqiao Building Moisturizing Chemical Factory should be firstly according to Chinese Pharmacopoeia