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目的了解淅川县接受免费抗病毒治疗患者治疗效果。方法利用国家艾滋病(AIDS)抗病毒治疗信息系统,收集淅川县2010—2015年正在治疗的AIDS患者基本信息和随访信息,统计分析不同时间段CD4+T淋巴细胞水平、病毒载量、机会性感染、病死率的变化及耐药情况。结果 339例抗病毒治疗患者以治疗时间分组,各组治疗后CD4+T淋巴细胞水平均有增加(P<0.01),CD4+T淋巴细胞呈上升趋势;治疗后病毒完全抑制率为76.31%,病毒抑制随治疗时间延长而增高;治疗后机会性感染发病率降低,病死率呈现出明显的下降趋势,出现低度耐药水平。结论淅川县AIDS患者接受抗病毒治疗效果较好。
Objective To understand the treatment effect of patients receiving free antiviral therapy in Xichuan County. Methods The information system of AIDS antiviral therapy was used to collect basic information and follow-up information of AIDS patients undergoing treatment from 2010 to 2015 in Xichuan County. The levels of CD4 + T lymphocytes, viral load, opportunistic infections at different time points were statistically analyzed. , Changes in mortality and drug resistance. Results 339 patients with antiviral therapy were divided into treatment time groups. The levels of CD4 + T lymphocytes increased (P <0.01) and the numbers of CD4 + T lymphocytes increased after treatment. The complete inhibition rate of virus after treatment was 76.31% The virus inhibition increased with the prolongation of treatment time; the incidence of opportunistic infections decreased after treatment, the mortality showed a significant downward trend, a low level of resistance. Conclusion AIDS patients in Xichuan County are better treated with antiviral therapy.