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目的探讨双源CT(DSCT)Flash模式低电压、低浓度碘对比剂联合正弦图确定迭代重组(SAFIRE)在冠状动脉成像中的可行性。方法 64例行冠状动脉CT血管成像(CCTA)检查的患者随机分为A组(n=32,100k V,350 mg I/ml)和B组(n=32,80 k V,270 mg I/ml),B组图像经SAFIRE重组后获得C组,A组和B(C)组均采用Flash模式扫描。由2名放射科医师对照分析3组图像质量及辐射剂量。结果 A组和B(C)组患者的年龄、体质量指数(BMI)、平均心率比较差异无统计学意义(P>0.05),B(C)组的容积剂量指数(CTDIvol)、有效剂量长度乘积(DLP)和有效剂量(ED)明显低于A组(P<0.05)。A组和C组冠状动脉节段图像质量评分、噪声(SD)、信噪比(SNR)和对比噪声比(CNR)比较差异无统计学意义(P>0.05),但A组和B组、B组和C组间比较差异有统计学意义(P<0.05)。结论 CCTA在Flash模式下,低电压、低浓度碘对比剂联合SAFIRE技术的图像质量能满足诊断要求,而且能显著降低患者辐射剂量和不良反应发生。
Objective To investigate the feasibility of dual-source CT (DSCT) Flash mode low-voltage, low-concentration iodine contrast agent combined with sinogram in determining coronary artery imaging using iterative recombination (SAFIRE). Methods Sixty-four patients undergoing coronary CT angiography (CCTA) were randomly divided into two groups: group A (n = 32,100k V, 350 mg I / ml) and group B (n = 32,80 k V, 270 mg I / ), Group B images were obtained after SAFIRE recombination group C, Group A and B (C) group were scanned using Flash mode. Three radiologists analyzed the image quality and radiation dose of two radiologists. Results There was no significant difference in age, body mass index (BMI) and average heart rate between group A and group B (C) (P> 0.05), volume index of dose (CTDIvol), length of effective dose Product (DLP) and effective dose (ED) were significantly lower than those in group A (P <0.05). There was no significant difference in image quality score, noise (SD), signal to noise ratio (SNR) and contrast to noise ratio (CNR) between group A and group C (P> 0.05) There was significant difference between group B and group C (P <0.05). Conclusion CCTA in Flash mode, low voltage, low concentration of iodine contrast agent combined with SAFIRE image quality to meet the diagnostic requirements, but also significantly reduce the patient’s radiation dose and adverse reactions.