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目的评估回收式自体输血对产科手术患者血液流变学和凝血功能的影响。方法选择拟行腹部手术的患者50例,分为自体输血组(A组)和异体输血组(B组)。输血前及输血后分别观察2组患者的血液流变学、凝血功能变化。结果 2组输血后红细胞计数、血细胞比容较输血前明显下降(P<0.05)。红细胞聚集性、红细胞刚性,全血粘度、血浆粘度等指标在输血前后差异均无统计学意义(P>0.05);输血后1 h 2组FIB及血小板计数均显著降低(P<0.05),但APTT、PT及ACT均明显延长(P<0.05)。结论回收式自体输血可维持产科手术患者血液流变学的稳定,对凝血功能的影响与异体输血无明显差异。
Objective To evaluate the effect of reclaimed autologous blood transfusion on the hemorheology and coagulation function of obstetric patients. Methods Fifty patients undergoing abdominal surgery were selected and divided into autologous blood transfusion group (A group) and allogenic transfusion group (B group). The blood rheology and coagulation function of two groups were observed before transfusion and after transfusion. Results After transfusion, the number of erythrocyte and hematocrit decreased significantly in both groups (P <0.05). There was no significant difference in the indexes of erythrocyte aggregation, erythrocyte rigidity, whole blood viscosity and plasma viscosity before and after transfusion (P> 0.05). The FIB and platelet count in 1 h after transfusion decreased significantly (P <0.05) APTT, PT and ACT were significantly prolonged (P <0.05). Conclusion Regenerative autologous blood transfusion can maintain the stability of hemorheology in patients undergoing obstetric surgery. There is no significant difference between coagulation function and allogeneic blood transfusion.