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目的分析美托洛尔对慢性心力衰竭患者心肌重构及心脏功能的影响。方法选取本院2013年10月~2014年10月收治的慢性心衰患者220例为研究对象,随机将其分为对照组和观察组,各110例。对照组患者仅给予常规基础治疗,观察组患者在对照组治疗基础上给予美托洛尔治疗,比较两组患者的疗效。结果观察组总有效率为94.55%,高于对照组的74.55%,差异有统计学意义(x2=17.5782,P<0.05);两组患者的超声指标、治疗后心率及6 min步行距离比较,差异有统计学意义(P<0.05)。结论美托洛尔辅助治疗慢性心力衰竭患者,可有效改善患者心肌重构和心脏功能,疗效显著,值得临床推广运用。
Objective To analyze the effects of metoprolol on myocardial remodeling and cardiac function in patients with chronic heart failure. Methods A total of 220 patients with chronic heart failure who were treated in our hospital from October 2013 to October 2014 were selected as the research object and randomly divided into control group and observation group, with 110 cases in each group. Patients in the control group were given routine basic treatment only. Patients in the observation group were treated with metoprolol on the basis of the control group, and the curative effect was compared between the two groups. Results The total effective rate in the observation group was 94.55%, which was higher than that in the control group (74.55%), the difference was statistically significant (x2 = 17.5782, P <0.05). The ultrasonic indexes, heart rate after treatment and walking distance at 6 minutes The difference was statistically significant (P <0.05). Conclusion Metoprolol adjuvant treatment of patients with chronic heart failure can effectively improve myocardial remodeling and cardiac function in patients with significant effect, worthy of clinical application.