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对１１８对不孕夫妇，拟采用ＩＵＩ前用ＨＯＰ系统检测男方精液，并以精子穿卵率为指标进行分组，统计ＩＵＩ的受孕率。结果：１１８例的４１２个治疗周期中，第一组：穿卵率≥１５％的患例，ＩＵＩ受孕率为４２％；第二组：１０％≤穿卵率＜１５％的患例，ＩＵＩ受孕率为１３％；第三组：穿卵率＜１０％者，ＩＵＩ受孕率为２％。第一组与第二、三组间其受孕率有明显差异，经统计学检验有显著意义（Ｐ＜０．００５）。结果表明，采用ＨＯＰ作为ＩＵＩ病例筛选指标，提高ＩＵＩ的成功率，对不孕症病因诊断与治疗具有重要的临床实用价值。
For 118 pairs of infertile couples, it is proposed to use the HOP system to test the male semen before IUI, and the sperm penetration rate is taken as the index to classify the IUI pregnancy rate. Results: Of the 412 treatment cycles of 118 cases, the first group was: the incidence of IUI conception was 42% in the case of penetrating rate≥15%; the second group was 10% ≤ the incidence of penetrating rate <15% The conception rate was 13%. The third group: the rate of IUI penetration was <10% and IUI conception rate was 2%. The first group and the second, the three groups of pregnancy rates were significantly different, statistically significant (P <0.005). The results show that the use of HOP as a screening index for IUI cases, to improve the success rate of IUI, has an important clinical value of diagnosis and treatment of infertility.