本文报道1968～1974年用硫唑嘌呤治疗原发性胆汁性肝硬化的结果。作者将45例有症状的原发性胆汁性肝硬化前期患者随机分为治疗组(22例)和对照组(23例)。凡已确诊为肝硬化、无症状或有肝功能衰竭、慢性或复发性化脓性感染和已接受免疫抑制剂治疗者,均经剔除。 This article reports the results of treatment of primary biliary cirrhosis with azathioprine from 1968 to 1974. The authors randomized 45 patients with symptomatic primary biliary cirrhosis to treatment (n = 22) and control (n = 23). Those who have been diagnosed with cirrhosis, asymptomatic or have liver failure, chronic or recurrent purulent infection and who have received immunosuppressive therapy, were rejected.