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随着对儿童鼻窦炎发病中免疫学因素的认识,使包括合成分泌型免疫球蛋白 A(SIgA)的局部免疫状态具有重要意义。SIgA 作用于细菌的感受器,阻碍其在上呼吸道粘膜表面的停留与繁殖。SIgA 的合成分几个阶段,皮下组织浆细胞合成类似血清 IgA 的亚型,赋予 SIgA 特异作用的分泌片是由粘膜上皮细胞合成的。激光照射能促进免疫球蛋白的合成。作者对120例6～15岁的上颌窦炎患儿行低频氦氖激光照射上颌窦粘膜,观察上颌窦冲洗液内 SIgA 水平
With the recognition of immunological factors in the pathogenesis of childhood sinusitis, the local immune status including the synthesis of secreted immunoglobulin A (SIgA) is of great importance. SIgA acts on bacterial receptors, hindering its stay in the upper respiratory tract mucosa and reproduction. SIgA synthesis in several stages, subcutaneous plasma cells similar to the synthesis of serum IgA subtype, SIgA secretion-specific role in the mucosal epithelial cells synthesized. Laser irradiation can promote the synthesis of immunoglobulin. The author of 120 cases of children aged 6 to 15 years of children with maxillary sinusitis underwent low-frequency He-Ne laser irradiation of maxillary sinus mucosa observed in maxillary sinus fluid SIgA levels