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目的:了解武汉地区β-内酰胺类复方制剂使用情况,为合理用药提供依据。方法:对武汉地区32家医院2009～2011年β-内酰胺类复方制剂使用数量、消耗金额、用药频度(DDDs)和日均费用(DDC)进行统计分析。结果:2009～2011年头孢菌素类复方制剂销售额呈增长趋势,年增幅平均在34%以上,而青霉素类复方制剂多呈下降趋势,但阿莫西林/克拉维酸3年中用药频度始终居于首位。结论:随着抗菌药耐药情况日益严重,β-内酰胺类复方制剂抗菌药使用的合理性和经济学指标有待深入评价。
OBJECTIVE: To understand the use of β-lactam compound preparations in Wuhan and provide the basis for rational drug use. Methods: The use quantity, consumption amount, DDDs and DDC of β-lactams in 32 hospitals in Wuhan from 2009 to 2011 were analyzed statistically. Results: The sales of cephalosporin compound preparations increased from 2009 to 2011, with an average annual increase of more than 34%, while the penicillin compound preparations showed a downward trend, but the frequency of amoxicillin / clavulanic acid treatment in three years Always be in the first place. Conclusion: With the increasingly serious antimicrobial resistance, the rationality and economic indicators of antimicrobial use of β-lactam compound remain to be further evaluated.