Landslide prediction is one of the most important aspects of prevention and control for geological hazards and the environmental protection. In order to study the nonlinear methods for landslide prediction, the synergetic-bifurcated model of predicting the timing of slope failure is established by combining Synergetics with Bifurcation Theory based on single-state variable friction law in this paper. The synergetic effects and bifurcated process of the factors in the slope evolution can be characterized in the model. Taking the Xintan Landslide as an example, the prediction of landslide is carried out based on the model suggested.