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抗结核药物副反应种类较多,虽多数不必中止治疗,但个别副反应处理不当可以产生严重后果,甚至死亡。本例为老年患者对多种抗结核药物有过敏反应。现报告如下: 病例:男性,67岁。9年中曾多次在成都市多家医院就诊,均诊断为双上肺陈旧性结核、肺气肿。在此期间,曾多次咯血或痰中带血、发烧而住院治疗。每次住院治疗及自服1种或2种抗结核药后出现寒战、高烧(39℃以上),而多为间断治疗,不规律用过SHREZ(S-链霉素、H-异烟肼、R-利福平、E-乙胺丁醇、Z-吡嗪酰胺)等药物。最短10d,最长达3个月。1999-04因反复发热90多天,以发热待查收治于四川省人民医院。行右侧附睾切除术,经病理证实为附睾结核,给予SHR治疗。5月上旬因咳嗽、发热(午后潮热)、乏力、头昏来我所就诊。
There are many types of side effects of anti-tuberculosis drugs, although most do not have to suspend treatment, but improper handling of individual side effects can have serious consequences, and even death. This case is an elderly patient allergic to a variety of anti-TB drugs. The report is as follows: Case: Male, 67 years old. In the past nine years, many hospitals in Chengdu have been diagnosed with double-lung obsolete tuberculosis and emphysema. During this period, he had multiple hemoptysis or sputum bloody, fever and hospitalization. Chlamydia and fever (above 39 ° C) occurred after each hospitalization and self-administration of one or two anti-TB drugs, mostly intermittent treatment, and irregular SHREZ (S-streptomycin, R-rifampicin, E-ethambutol, Z-pyrazinamide) and other drugs. The shortest 10d, up to 3 months. 1999-04 due to repeated fever for more than 90 days, with fever to be investigated and treated in Sichuan Provincial People’s Hospital. Right epididymoidectomy confirmed by pathological epididymal tuberculosis, given SHR treatment. In early May due to cough, fever (afternoon hot flashes), fatigue, dizziness, I came to the clinic.