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本文分析长期口服维拉帕米或硝苯啶对57.3±10.9(43~75)岁的10(男9、女1)例慢性稳定型心绞痛(4.4±4.1年)患者左室功能的影响。本组内4例曾有心肌梗塞史(其中1例曾作冠状动脉搭桥术),无一例有左心衰竭表现,活动平板试验均阳性。随机分组后:一组先服维拉帕米(120mg,tid)4周,继服硝苯啶(20mg,qid)4周;另一组服药顺序相反。其中1例因症状性低血压而仅能服较小剂量硝苯啶(10mg,qid)。服药前、服药第4周和第8周未次服药后3小时,进行静息时和运动时(症状限制性立位
This article analyzes the effects of long-term oral verapamil or nifedipine on left ventricular function in 57.3 ± 10.9 (43-75) years of 10 (9, 1) women with chronic stable angina (4.4 ± 4.1) years. Four patients in this group had a history of myocardial infarction (one of them had coronary artery bypass grafting), and none of them had left ventricular failure. All patients were positive in activity plate test. After randomization, one group received verapamil (120 mg, tid) for 4 weeks followed by 4 weeks of nifedipine (20 mg qid); the other group received the opposite order. One case of symptomatic hypotension and only take smaller doses of nifedipine (10mg, qid). Before taking medicine, taking medicine for the fourth week and the eighth week did not take the medicine 3 hours after the rest and during exercise (the symptom restrictive standing position