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患者,男,5岁.1994年7月8日,因颈部长疖肿并发全身化脓性感染,住进我院小儿科.给予头孢唑啉抗感染,tid,iv,每次0.5g,并将颈部脓肿切开,用3%双氧水棉球清洗,采用盐水纱条引流,每天用上述方法换药1次.3天后,症状好转,T.P.R均正常.颈部切口亦无脓液流出.继续给予头孢唑琳肌注,0.5g/次,bid,颈部引流取消,改用酒精棉球消毒后换药,qd.换药后约半小时,护士发现患者颜面发红,呼吸急促、大汗、口唇发绀,立即给氧,半小时后症状消失,停止吸氧,亦未出现不正常情况.第2天,注射头孢唑啉后,另一名值班护士替患者换药,方法同昨天,约20min后,患者出现了同样的症状,仍给予吸氧,未作任何处理,大约30min后症状消失,小孩安然入睡.医生考虑为药物不良反应,根据病史,将酒精消毒改用生理盐水消毒,再未出现上述反应,治疗4天后痊愈出院.
Patient, male, 5 years old .In July 8, 1994, due to neck length carbuncle complicated by systemic purulent infection, admitted to our hospital pediatric .Certazoline anti-infective, tid, iv, each 0.5g, and Neck abscess incision, with 3% hydrogen peroxide cotton ball cleaning, drainage with saline gauze, the dressing method 1 day .3 days later, the symptoms improved, TPR are normal .No pus neck incision outflow. Continue to give Cefazolin intramuscular injection, 0.5g / time, bid, neck drainage cancel, use alcohol cotton ball disinfection after dressing, qd. About half an hour after dressing change, the nurse found that patients face redness, shortness of breath, sweating, Lips cyanosis, immediately give oxygen, half an hour later symptoms disappear, stop oxygen, nor an abnormal situation .2 days after cefazolin injection, another on duty nurse dressing for patients, the method with yesterday, about 20min After the patient had the same symptoms, still given oxygen, without any treatment, the symptoms disappear after about 30min, the child safely sleep. Doctors consider adverse drug reactions, according to medical history, the alcohol disinfection instead of saline disinfection, and then not Appear above reaction, cured 4 days after discharge.