糖尿病的各种并发症,尤其心血管并发症是糖尿病患者致死和致残的主要原因。维生素D与糖尿病血管并发症的发生关系密切,其通过多种途径对糖尿病肾病起保护作用,与糖尿病心血管疾病的发生及病死率明显相关,并且在血管钙化中可能有一定作用。维生素D受体多态性与糖尿病视网膜病变有密切联系,适当补充维生素D可以减少糖尿病血管并发症。 Various complications of diabetes, especially cardiovascular complications, are the leading cause of death and disability in diabetic patients. Vitamin D is closely related to the occurrence of diabetic vascular complications. It has a protective effect on diabetic nephropathy through various pathways, which is obviously related to the occurrence and mortality of diabetic cardiovascular diseases and may play a role in vascular calcification. Vitamin D receptor polymorphism and diabetic retinopathy are closely linked, appropriate vitamin D can reduce diabetic vascular complications.