本研究在超微结构水平上证明了猪胆汁提取物及其有效成份去氧胆酸钠对培养的人阴道毛滴虫具有碎解作用,鞭毛及尾突断离,质膜及内膜系统如吞噬小体和氢化小体的界膜、核膜等破损,细胞质凝集,乃至整个虫体完全碎解。其作用机制可能与药物的表面活性作用促进了滴虫生物膜系统结构脂类的降解直接有关。 In this study, it was demonstrated at the ultrastructural level that the extract of pig bile and its effective ingredient, sodium deoxycholate, have a disintegrating effect on the cultured human Trichomonas vaginalis, flagella and caudal process break off, and plasma membrane and endometrial system such as Damage to the confinement membrane and nuclear membrane of phagosomes and hydrogenated bodies, cytoplasm agglutination, and even the entire parasite breaks down. The mechanism of action may be directly related to the surface activity of the drug which promotes the degradation of structural lipids of the biofilm system of Trichomonas.