恶性血液病患儿化疗后常伴有免疫功能低下、中性粒细胞减少等骨髓抑制表现,是深部真菌感染的高危人群。恶性血液病患儿化疗后深部真菌感染呈现逐年上升趋势,是儿童恶性血液系统疾病治疗失败的常见原因,受到广泛关注[1]。及时选择安全有效的抗真菌药物治疗是整体治疗 After chemotherapy in children with hematologic malignancies often accompanied by immune dysfunction, neutropenia and other bone marrow suppression performance, is a high risk of deep fungal infection in the crowd. Deep fungal infection in children with hematologic malignancies shows a trend of increasing year by year, which is a common cause of failure in the treatment of children with hematologic malignancies and has received extensive attention [1]. Timely selection of safe and effective antifungal drug treatment is the overall treatment