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对蚯蚓纤溶酶进行了哈白兔体内、体外溶栓、抗凝试验,分别以蛇毒抗栓酶和尿激酶不同剂量组作对照试验,均有显著的溶解血栓功能.另外,蚯蚓纤溶酶溶解天然血块,对纤维蛋白原含量及凝血时间影响的药理学试验,结果证明蚯蚓纤溶酶具有溶栓与抗凝作用.
In vitro and in vivo thrombolytic and anticoagulant tests were performed on fibrinolytic enzymes in rabbits. The venom antithrombotic enzyme and different doses of urokinase were used as control experiments. Both had significant thrombolytic activity. In addition, fibrinolytic enzymes The pharmacological test of the effect of dissolving the natural blood clots on the fibrinogen content and clotting time showed that fibrinolytic enzymes had thrombolytic and anticoagulant effects.